Make A Webcomic Or Webtoon

So, I've been scripting my first webtoon idea, and I started storyboarding a little too. Buuuut-- I was wondering what kind of style I would use. Like, different authors have different styles, in both art and layout. I'd say wolf in the house was the most unique one,as well as dead or alive.
What is your preference or what you like when it comes to style or layout? Anything specific or unique.. or even the artstyle, example the coloring or lineart.