Couples that in your opinion have no chemistry?

Which couples in your opinion have no business existing because they make no sense, but more importantly, they have no chemistry?

Here are some of mine:

In general most shojo where the guy is cool and collected and good in school
and the girl is a bonafide idiot.

More specific;
Usagi and Mamoru (aka Serena and Darien)- I don’t care that they’re soulmates or lovers from a previous life, what exactly could have a college aged teenager find attractive or interesting about a 14-year old loud mouth crybaby?

Tohru’s parents- Again, what besides her brokenness attracted Katsuya to Kyoko? Both of them were messed up in the head so in some twisted way I can see how he would find Kyoko “entertaining”, but what about after the newness wore off?

Kureno and Uo- I don’t believe he was in love with her. He’s a sheltered man with a truncated childhood who attached himself to the first person outside of his cage that was nice to him and she was a teenager who was flattered that this handsome older guy was “in love” with her.

Ichigo and Orihime- no sexual tension at least on his part. He has more
chemistry with Yoruichi.

Sakura and Sasuke- the quintessential wtf? Couple. We’ve all already heard that argument, but he definitely had more chemistry with Naruto (even if it wasn’t romantic).