Responses
With Garou being a fan favorite I dont see Saitama killing him.
Even more so since Garou is more human than monster.
Though Im not sure if there were differences between the ONE version and his. At least when it comes to story
this is a spoiler for those who didn't read ONE's original webcomic
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if, this version follows the original with the Garou fight, you don't have to worry about Garou. Saitama and him will fight, Garou will become a monster, but Saitama won't kill Garou, and Garou will somehow revert to his human form. let's all just hope Murata follows the original on this one :"))